Product ID:CELL-DYN 4000 WBC REAGENT, PART B, 01H78-01
MSDS Date:12/22/1998
FSC:6550
NIIN:00N091332
Status Code:A
MSDS Number: CJJJP

ABBOTT LABORATORIES

100 ABBOTT PARK RD
ABBOTT PARK, IL 60064-3500
US

Emergency Phone: 847-937-7970

Info Phone: 847-937-3386

Cage: 33110

ABBOTT LABORATORIES INC DIAGNOSTICS DIV

NORTH CHICAGO, IL 60064 US

Telephone: 847-935-7177

Cage: 33110

AMMONIUM CHLORIDE

CAS: 12125-02-9

RTECS: BP4550000

OSHA PEL N/K

ACGIH TLV: 10 MG/M3

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

FORMALDEHYDE

CAS: 50-00-0

RTECS: LP8925000

OSHA PEL see 1910.1048

ACGIH TLV: N/K

EPA Report Quantity: 100 LBS

DOT Report Quantity: 100 LBS

WATER

CAS: 7732-18-5

RTECS: ZC0110000

OSHA PEL N/K

ACGIH TLV: N/K

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFORMATION.
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:YES
Health Hazards Acute and Chronic:NO ROUTES OF ENTRY ANTICIPATED WHEN
USED AS DIRECTED. SENSITIZER BY DERMAL CONTACT. AMMONIUM CHLORIDE:
IN CLINICAL USE, THIS MATERIAL ADDS AMMONIUM & CHLORIDE IONS TO THE
BODY. FORMALDEHYDE VAPOR HAS BEEN REPORTED TO CAUSE RESPIRATORY
IRRITATION AT CONCENTRATIONS >0.1 PPM IN HUMANS. AT HIGHER
CONCENTRATIONS (50 PPM), PULMONARY EDEMA & DEATH HAS BEEN REPORTED
IN ANIMALS. REPEATED CONTACT WITH VAPOR REPORTED TO CAUSE
RESPIRATORY SENSITIZATION. PRIMARY IRRITANT EFFECT: ON THE
SKIN/EYES: NO IRRITANT EFFECT. SENSITIZATION POSSIBLE THROUGH SKIN
CONTACT. TARGET ORGANS/SYSTEMS: SKIN, DNA, GASTROINTEST INAL TRACT,
HEMATOPOIETIC SYSTEM.
Explanation of Carcinogenicity:FORMALDEHYDE: IARC MONOGRAPHS,
SUPPLEMENT, VOLUME 62, PAGE 217, 1995: GROUP 2A. NTP 8TH ANNUAL
REPORT ON CARCINOGENS, 1998: REASONABLY ANTICIPATED TO BE HUMAN
CARCINOGEN. OSHA REGULATED: CFR 29 1910.1 048. ANIMAL: NASAL
TUMORS.
Effects of Overexposure:SEE HEALTH HAZARDS.
Medical Cond Aggravated by Exposure:PREEXISTING SKIN AILMENTS; SKIN
ALLERGIES; PREEXISTING GASTROINTESTINAL TRACT AILMENTS; PREEXISTING
HEMATOPOIETIC AILMENTS.

First Aid:NO SPECIAL MEASURES REQUIRED EXCEPT AS NOTED BELOW: INHAL:
REMOVE FROM SOURCE OF EXPOS. IF SIGNS OF TOXICITY OCCUR, SEEK MED
ATTN. PROVIDE SYMPTOMATIC/SUPPORTIVE CARE AS NEEDED. SKIN: REMOVE
FROM SOUR CE OF EXPOS. FLUSH W/COPIOUS AMTS OF WATER. IF IRRIT
PERSISTS/SIGNS OF TOXICITY OCCUR, SEEK MED ATTN. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEC. EYES: REMOVE FROM SOURCE OF
EXPOS. FLUSH W/COPIOUS AMT S OF WATER FOR AT LEAST 15 MINS. IF
IRRIT PERSISTS/SIGNS OF TOXICITY OCCUR, SEEK MED ATTN. PROVIDE
SYMPTOMATIC/SUPPORTIVE CARE AS NEC. INGEST: REMOVE FROM SOURCE OF
EXPOS. IF SIGNS OF TOXICITY OCCUR, SEEK MED ATTN. (SUP DAT)

Extinguishing Media:CARBON DIOXIDE, EXTINGUISHING POWDER OR WATER
SPRAY. FIGHT LARGER FIRES WITH WATER SPRAY OR ALCOHOL RESISTANT
FOAM.
Fire Fighting Procedures:NO SPECIAL MEASURES REQUIRED. WEAR NIOSH
APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:PRODUCT IS NOT SELFIGNITING. PRODUCT DOES
NOT PRESENT AN EXPLOSION HAZARD.

Spill Release Procedures:WEAR PROTECTIVE EQUIPMENT (SEE CONTROL
MEASURES SECTION). KEEP UNPROTECTED PERSONS AWAY. PREVENT LIQUID
AND VAPOR FROM ENTERING INTO SEWAGE SYSTEM, WORKPITS AND CELLARS.
CONTAIN SPILL WITH APPROPRIATE ABSORBENT MATERIAL. ABSORB WITH
LIQUID-BINDING MATERIAL (SAND, DIATOMITE, ACID BINDERS, UNIVERSAL
BINDERS, SAWDUST). NO DANGEROUS SUBSTANCES ARE RELEASED.

Handling and Storage Precautions:AVOID CONTACT WITH SKIN. NO SPECIAL
MEASURES REQUIRED ABOUT PROTECTION AGAINST EXPLOSIONS AND FIRES. NO
SPECIAL REQUIREMENTS TO BE MET BY STOREROOMS AND RECEPTACLES.
INFORMATION ABOUT STORAGE IN ONE C OMMON STORAGE FACILITY: NOT
REQUIRED.
Other Precautions:PROTECT FROM HEAT AND DIRECT SUNLIGHT. STORAGE CLASS:
NOT APPLICABLE. CLASS ACCORDING TO REGULATION ON FLAMMABLE LIQUIDS:
NOT APPLICABLE.

Respiratory Protection:NOT NECESSARY IF ROOM IS WELL-VENTILATED. THE
APPROPRIATE RESPIRATORY PROTECTION SHOULD BE USED IF AIRBORNE
CHEMICAL CONCENTRATION EXCEEDS THE EXPOSURE LIMITS LISTED. WEAR
NIOSH APPROVED RESPIRATOR AP PROPRIATE FOR EXPOSURE OF CONCERN .
Protective Gloves:WEAR CHEMICALLY RESISTANT GLOVES IF HAND CONTACT
W/THE MATERIAL IS ANTICIPATED.
Eye Protection:NOT REQUIRED. ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYEWASH & DELUGE SHOWER MTG ANSI DESIGN
CRITERIA . BODY PROTECTION NOT NEEDED FOR SMALL QUANTITY USAGE. THE
NEED FOR THE APPROPRIATE BODY PROTECTION SHOULD BE DETERMINED ON A
CASE BY CASE BASIS.
Work Hygienic Practices:IMMEDIATELY REMOVE ALL SOILED AND CONTAMINATED
CLOTHING. WASH HANDS BEFORE BREAKS AND AT THE END OF WORK.
Supplemental Safety and Health
FIRST AID PROCEDURES: PROVIDE SYMPTOMATIC/SUPPORTIVE CARE AS NECESSARY.
INFORMATION FOR DOCTOR: THE FOLLOWING SYMPTOMS MAY OCCUR: ALLERGIC
REACTIONS, CRAMPS, GASTRIC OR INTESTINAL DISORDERS, NAUSEA.

Boiling Pt:=100.C, 212.F
Melt/Freeze Pt:M.P/F.P Text:NOT DETERMINED
Vapor Pres:23.0 HPA @ 20C
pH:2.5 @ 20C
Solubility in Water:FULLY MISCIBLE
Appearance and Odor:COLORLESS LIQUID; ODORLESS.

Stability Indicator/Materials to Avoid:YES
NO DANGEROUS REACTIONS KNOWN.
Stability Condition to Avoid:NO DECOMPOSITION IF USED ACCORDING TO
SPECIFICATIONS.
Hazardous Decomposition Products:NO DANGEROUS DECOMPOSITION PRODUCTS
KNOWN.

Waste Disposal Methods:PRODUCT: RECOMMENDATION: DISPOSE IN ACCORDANCE
WITH FEDERAL, STATE AND LOCAL REGULATIONS. UNCLEANED PACKAGINGS:
RECOMMENDATION: DISPOSE IN ACCORDANCE WITH FEDERAL, STATE AND LOCAL
REGULATIONS. RECOMME NDED CLEANSING AGENT: WATER, IF NECESSARY WITH
CLEANSING AGENTS.

Toxicological Information:ACUTE TOX: LD/LC50 VALUES FOR HAZ INGS PER
OSHA CRITERIA: COMPONENTS (100% PURE SUBSTANCE/S): 12125-02-9
AMMONIUM CHLORIDE: ORAL: LD50: 1000-1650 MG/KG (MAMMAL). IN RATS,
MICE & RABBITS. LDLO 2000 IN INFANTS. TARGET ORGAN EFTS: CLINICAL
(HUMAN). 50-00-0 FORMALDEHYDE: ORAL: LD50: 100 MG/KG (RAT). LD50
FOR 37% FORMALDEHYDE SOLN=100 MG/KG IN RATS. DERMAL: LD50: 270
MG/KG (RABBITS). LD50 FOR 37% FORMA LDEHYDE SOLN=270 MG/KG IN
RABBITS. INHAL: LC50/ 1H: 1 PPM (SCH). TCLO (CARCIN): 15 PPM
(MAMMAL). RATS & MICE EXPOSED CHRONICALLY TO 15 PPM FORMALDEHYDE
DEVELOPED NASAL TUMORS. TARGET ORGAN EFTS: > 0.1 PPM (HUMAN).
(OTHER INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:GENERAL NOTES: DO NOT ALLOW UNDILUTED PRODUCT OR LARGE
QUANTITIES OF IT TO REACH GROUND WATER, WATER COURSE OR SEWAGE
SYSTEM.

Transport Information:DOT REGULATIONS: REMARKS: NOT REGULATED FOR
TRANSPORTATION. LAND TRANSPORT ADR/RID (CROSS-BORDER): REMARKS: NOT
REGULATED FOR TRANSPORTATION; MARINE POLLUTANT: NO; REMARKS: NOT
REGULATED FOR TRANSPORT ATION. ICAO/IATA: REMARKS: NOT REGULATED
FOR TRANSPORTATION.

SARA Title III Information:SARA (SUPERFUND AMENDMENTS AND
REAUTHORIZATION ACT OF 1986 - USA): SECTION 302/304 (40 CFR 355.30
/ 40 CFR 355.40): 50-00-0 FORMALDEHYDE; SECTION 313 (40 CFR
372.65): 50-00-0 FORMALDEHYDE.
Federal Regulatory Information:MARKINGS ACCORDING TO EUROPEAN
GUIDELINES: THE PRODUCT HAS BEEN CLASSIFIED AND LABELLED IN
ACCORDANCE WITH APPLICABLE EUROPEAN COMMUNITY (EC) DIRECTIVES. CODE
LETTER AND HAZARD DESIGNATION OF PRODUCT: XI IRRITANT.
HAZARD-DETERMINING SUBSTANCE/S OF LABELLING: FORMALDEHYDE. RISK
PHRASES: 43 MAY CAUSE SENSITIZATION BY SKIN CONTACT. SAFETY
PHRASES: 2 KEEP OUT OF THE REACH OF CHILDREN; 24 AVOID CONTACT
WITH SKIN; 37 WEAR SUITABLE GLOVES; 46 IF SWALLOWED, SEEK MEDICAL
ADVICE IMMEDIATELY AND SHOW THIS CONTAINER OR LABEL.
State Regulatory Information:CALIFORNIA PROPOSITION 65 (USA): CHEMICALS
KNOWN TO CAUSE CANCER: 50-00-0 FORMALDEHYDE. CHEMICALS KNOWN TO
CAUSE REPRODUCTIVE TOXICITY: THE PRODUCT DOES NOT CONTAIN LISTED
SUBSTANCES.